Objective: Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use.
Methods: In thirty-two patients (31 pituitary adenomas and 1 meningioma) Bioglue was used to help reconstruct the sellar floor after endonasal transsphenoidal procedures between January 2001 and April 2002 at the Royal Melbourne Hospital.
Results: There were no post-operative CSF rhinorrhea, allergic rhinitis, meningitis, pneumocranium, granulomas or other complications associated with the use of Bioglue.
Conclusion: This technique of reconstruction of sellar floor using Bioglue is simple and time efficient in preventing CSF fistula formation following transsphenoidal procedures for sellar region lesions.