A percutaneous radial artery approach for coronary angiography was performed in 40 patients using a 5-F catheter. The patients, in whom the femoral artery approach was difficult or contraindicated because of advanced arteriosclerosis, were selected on the basis of easily palpable radial and ulnar arteries and a normal Allen test. In 1 patient the catheter could not be advanced to the brachial artery, and subsequently this patient underwent the brachial approach. In all 39 patients, selective left coronary angiography was accomplished using a left Judkins catheter, and the right coronary artery and the saphenous vein graft were entered successfully using a right Judkins or Amplatz catheter. All patients had excellent quality of images of coronaries and vein grafts. In 5 patients (13%), the pulse remained acutely diminished, but there were no evidences or complaints of pain. Bleeding at the puncture site occurred in 1 patient (3%), and 5 patients (13%) had subcutaneous bleeding around the puncture site. Pseudoaneurysm, nerve injury and arteriovenous fistula were not detected at the time of discharge.