Fast and slow parietal pathways mediate spatial attention

Nat Neurosci. 2004 Mar;7(3):217-8. doi: 10.1038/nn1203. Epub 2004 Feb 22.

Abstract

Mechanisms of selective attention are vital for guiding human behavior. The parietal cortex has long been recognized as a neural substrate of spatial attention, but the unique role of distinct parietal subregions has remained unclear. Using single-pulse transcranial magnetic stimulation, we found that the angular gyrus of the right parietal cortex mediates spatial orienting during two distinct time periods after the onset of a behaviorally relevant event. The biphasic involvement of the angular gyrus suggests that both fast and slow visual pathways are necessary for orienting spatial attention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attention / physiology*
  • Brain Mapping
  • Cues
  • Electric Stimulation / instrumentation
  • Functional Laterality / physiology
  • Humans
  • Magnetics
  • Nerve Net / anatomy & histology
  • Nerve Net / physiology
  • Neuropsychological Tests
  • Orientation / physiology
  • Parietal Lobe / anatomy & histology
  • Parietal Lobe / physiology*
  • Perceptual Disorders / physiopathology
  • Photic Stimulation
  • Psychomotor Performance / physiology
  • Reaction Time / physiology*
  • Space Perception / physiology*
  • Visual Fields / physiology
  • Visual Pathways / anatomy & histology
  • Visual Pathways / physiology*