Neuroimaging in disorders of cortical development

Neuroimaging Clin N Am. 2004 May;14(2):231-54, viii. doi: 10.1016/j.nic.2004.03.003.

Abstract

Malformations of cortical development are important causes of developmental delay and epilepsy. They are classified by the presumed stage during which normal development is interrupted: neuronal proliferation and differentiation, neuronal migration, and late migration/cortical organization. This article discusses the important malformations in each of these groups, how and why the malformations develop, and their imaging findings. A better understanding of these disorders helps in genetic counseling of the parents and may help in the treatment of associated epilepsy.

Publication types

  • Review

MeSH terms

  • Cerebral Cortex / abnormalities*
  • Cerebral Cortex / embryology*
  • Humans
  • Nervous System Malformations / diagnostic imaging
  • Nervous System Malformations / embryology*
  • Nervous System Malformations / pathology*
  • Radiography