Reversible posterior leukoencephalopathy, cerebral vasoconstriction, and strokes after intravenous immune globulin therapy in guillain-barre syndrome

Christine E Doss-Esper; Aneesh B Singhal; Marsha S A Smith; Galen V Henderson

doi:10.1177/1051228404273820

Reversible posterior leukoencephalopathy, cerebral vasoconstriction, and strokes after intravenous immune globulin therapy in guillain-barre syndrome

J Neuroimaging. 2005 Apr;15(2):188-92. doi: 10.1177/1051228404273820.

Authors

Christine E Doss-Esper¹, Aneesh B Singhal, Marsha S A Smith, Galen V Henderson

Affiliation

¹ Department of Neurology, Division of Critical Care and Emergency Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02114, USA.

PMID: 15746232
DOI: 10.1177/1051228404273820

Abstract

The authors report a patient with Guillain-Barré syndrome who developed acute hypertension, reversible posterior leukoencephalopathy syndrome, ischemic and hemorrhagic strokes, and reversible cerebral arterial vasoconstriction shortly after initiating intravenous immune globulin therapy. Possible interrelationships and mechanisms of these complications are discussed.

Publication types

Case Reports

MeSH terms

Aged
Brain Diseases / etiology*
Brain Ischemia / etiology
Cerebral Hemorrhage / etiology
Diffusion Magnetic Resonance Imaging
Female
Guillain-Barre Syndrome / therapy*
Humans
Hypertension / etiology
Immunoglobulins, Intravenous / adverse effects*
Magnetic Resonance Imaging
Stroke / etiology*
Vasospasm, Intracranial / etiology*

Substances

Immunoglobulins, Intravenous