Contemporary imaging techniques for the diagnosis of renal artery stenosis

Eur Radiol. 2005 Nov;15(11):2219-29. doi: 10.1007/s00330-005-2826-6. Epub 2005 Jun 28.

Abstract

Renal artery stenosis (RAS) is a potentially curable cause of renovascular hypertension (RVH) and is caused by either atherosclerosis or fibromuscular dysplasia (FMD) in the vast majority of patients. Although intra-arterial digital subtraction angiography (IA-DSA) is still considered the standard of reference test for the anatomical diagnosis of RAS, noninvasive techniques such as MR angiography, CT angiography, and color-aided duplex ultrasonography are promising alternatives that also allow functional characterization of RAS. We provide an overview of these techniques and discuss their relative merits and shortcomings. Analysis of high-quality studies shows that both MR and CT angiography are significantly more accurate for the diagnosis of at least 50% atherosclerotic RAS than ultrasonographic techniques. The primary strength of ultrasonography at present is its suggested ability to predict functional recovery based on preinterventional resistance index measurements. A still unresolved issue is the detection of FMD. Because missing RVH may have serious consequences the most important requirement for a screening test is that it has high sensitivity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Angiography / methods
  • Humans
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Renal Artery Obstruction / diagnosis*
  • Renal Artery Obstruction / diagnostic imaging
  • Tomography, X-Ray Computed
  • Ultrasonography