[Endovascular treatment of non-ruptured intracranial aneurysms: critical analysis of the literature]

J Neuroradiol. 2008 May;35(2):116-20. doi: 10.1016/j.neurad.2008.03.002. Epub 2008 May 7.
[Article in French]

Abstract

Background: The goal was to evaluate, from the published data, the results of the endovascular treatment of unruptured aneurysms.

Methods: We have searched Medline for studies publishing results for endovascular coiling of unrupured aneurysms. Studies were classified as single-center, multicenter, or meta-analysis.

Results: Single-center studies always underestimate morbidity and mortality rates. However, it is possible to estimate mortality rate around 1.5% and morbidity rate between 3 and 6%. Some published series have directly compared results of endovascular treatment with surgical treatment. The results are always in favour of endovascular treatment, demonstrating a lower rate of complications and lower total hospital charges.

Conclusion: All published series of unruptured aneurysms favour the endovascular treatment instead of surgery. However, there is a lack of multicenter prospective series evaluating the results of the endovascular treatment of unruptured aneurysms. Likewise, there is no scientific arguments demonstrating that preventive treatment of unruptured aneurysms decreases the mortality and allows to decrease the risk of neurologic sequellae.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Embolization, Therapeutic*
  • Humans
  • Intracranial Aneurysm / mortality
  • Intracranial Aneurysm / therapy*
  • Research Design