Arterial spin-labeled magnetic resonance imaging is a powerful method for generating quantitative cerebral perfusion data. Clinical adoption of this technique is hampered by the lack of availability of the final postprocessed images. This is predominantly due to the need for research personnel to handle image transfer, postprocessing, and image display/review. Here, we describe a fully automated pipeline for clinical implementation of a magnetic resonance spin-tag perfusion sequence that can be extended to any studies requiring off-line processing.