Selective embolization of unruptured intracranial aneurysms is associated with low retreatment rate

Neuroradiology. 2010 Feb;52(2):141-6. doi: 10.1007/s00234-009-0607-7. Epub 2009 Oct 13.

Abstract

Introduction: To report long-term imaging findings of 101 patients with 129 unruptured intracranial aneurysms (UIA) treated by embolization.

Methods: A retrospective review of our prospectively maintained database identified all patients with an UIA treated by embolization with coils only and with a minimal 12-month imaging follow-up. The clinical charts, procedural data, and angiographic results were reviewed.

Results: Between March 2004 and June 2009, 101 patients with 129 UIA were identified (71 women/30 men, mean age = 51.4 years). Ninety-four aneurysms (73%) were large (10-25 mm), and 35 (27%) were small (<10 mm). Aneurysms mean size was 10.7 mm (median, 9 mm; range 3-22 mm); 87 UIA (67.5%) had a small neck (<4 mm or neck/sac ratio < 0.7), and 42 (32.5%) had a wide neck (> or =4 mm or neck/sac ratio > or = 0.7). Selective coiling with bare/coated coils was performed in 125 cases and four cases, respectively. The balloon-assisted technique was used in 47 cases (36.4%). Only one patient experienced a symptomatic complication (thromboembolism) and kept a slight hemiparesis. Immediate results included 77 complete occlusions (59.7%), 45 neck remnants (34.9%), and 7 incomplete occlusions (5.4%). Mean imaging follow-up of 32 months showed 104 stable occlusions (80.6%), 12 further thrombosis (9.3%), 7 major recanalizations (5.4%), and 6 minor recanalizations (4.7%). Retreatment was required in seven wide-necked and/or large aneurysms including four treated with coated coils. No bleeding occurred during follow-up.

Conclusion: Selective embolization of UIA is associated with stable long-term anatomical results and low retreatment rate.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Balloon Occlusion / adverse effects
  • Balloon Occlusion / instrumentation
  • Balloon Occlusion / methods
  • Databases, Factual
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Intracranial Aneurysm / pathology
  • Intracranial Aneurysm / therapy*
  • Male
  • Middle Aged
  • Paresis / etiology
  • Postoperative Complications
  • Prospective Studies
  • Retreatment
  • Retrospective Studies
  • Thromboembolism / etiology
  • Time Factors
  • Treatment Outcome
  • Young Adult