Abstract
The truncular venous malformation (VM) represents an embryologically defective vein where developmental arrest has occurred during the vascular trunk formation period in the 'later stage' of the embryonic development. A relatively simple truncular VM lesion such as a venous web at the hepatic venous outlet causes portal hypertension giving a profound damage/impact to the liver. A similar condition involving the head and neck venous system may cause chronic cerebro-spinal venous insufficiency (CCSVI) and may be involved in the development or exacerbation of multiple sclerosis.
MeSH terms
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Animals
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Azygos Vein / abnormalities*
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Azygos Vein / physiopathology
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Chronic Disease
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Collateral Circulation
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Constriction, Pathologic
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Humans
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Jugular Veins / abnormalities*
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Jugular Veins / physiopathology
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Multiple Sclerosis / etiology
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Multiple Sclerosis / pathology
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Multiple Sclerosis / physiopathology
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Regional Blood Flow
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Spinal Cord / blood supply*
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Syndrome
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Vascular Malformations / complications*
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Vascular Malformations / pathology
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Vascular Malformations / physiopathology
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Venae Cavae / abnormalities*
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Venae Cavae / physiopathology
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Venous Insufficiency / etiology*
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Venous Insufficiency / pathology
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Venous Insufficiency / physiopathology