Visualization of endolymphatic hydrops in Ménière's disease with single-dose intravenous gadolinium-based contrast media using heavily T(2)-weighted 3D-FLAIR

Magn Reson Med Sci. 2010;9(4):237-42. doi: 10.2463/mrms.9.237.

Abstract

Heavily T(2)-weighted 3-dimensional fluid-attenuated inversion recovery (hT(2)W-3D-FLAIR) technique has been reported to be more sensitive than conventional 3D-FLAIR in detecting low concentrations of gadolinium-based contrast media (GBCM) in fluid. We applied hT(2)W-3D-FLAIR to visualize endolymphatic hydrops of Ménière's disease in 3 patients 4 hours after single-dose intravenous injection of GBCM and successfully visualized endolymphatic hydrops in either the cochlea or vestibule in all patients. This technique can be implemented in a clinical setting.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged, 80 and over
  • Cochlea / pathology
  • Contrast Media* / administration & dosage
  • Diagnosis, Differential
  • Endolymphatic Hydrops / complications
  • Endolymphatic Hydrops / pathology*
  • Female
  • Gadolinium
  • Heterocyclic Compounds* / administration & dosage
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Injections, Intravenous
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meniere Disease / complications*
  • Middle Aged
  • Observer Variation
  • Organometallic Compounds* / administration & dosage

Substances

  • Contrast Media
  • Heterocyclic Compounds
  • Organometallic Compounds
  • gadoteridol
  • Gadolinium