Carotid artery stenting in patients with symptomatic carotid stenosis: a single-center series

J Neuroradiol. 2013 Mar;40(1):38-44. doi: 10.1016/j.neurad.2012.03.003. Epub 2012 May 24.

Abstract

Objectives: Carotid angioplasty with stenting (CAS) in patients with carotid stenosis (CS) has become more restricted in France especially since the disclosure of such studies as EVA-3S and Stent-supported percutaneous angioplasty of the carotid artery versus endarterectomy (SPACE). This report is of a series of CS cases contraindicated for endarterectomy that underwent CAS at a French center of interventional neuroradiology.

Patients and methods: Fifty-five patients with symptomatic CS more than 60% consecutively submitted to CAS between September 2008 and February 2011. The primary endpoint was either death or stroke within 30 days of the procedure; a secondary goal was to identify any possible factors that might have influenced the success and outcome of the intervention.

Results: The overall periprocedural stroke/death rate at 30 days was 5.4% (three out of 55 patients), with three non-disabling strokes and no deaths. Twenty-seven patients (49.1%) were treated with a cerebral protection device (CPD). Stent placement was achieved in all cases. Open- and closed-cell stents were implanted in 40 (72.7%) and 15 procedures (27.3%), respectively. Neither the use of a CPD, the carotid stent cell design nor any anatomical or technical factors were associated with a lower risk of stroke or death within 30 days of CAS.

Conclusion: CAS in symptomatic patients with CS contraindicated for endarterectomy in this selected French series proved feasible and safe, with acceptable levels of morbidity. Use of a CPD, type of stent (open- or closed-cell), and anatomical and technical factors had no influence on the success of the procedure or the outcome within 30 days of the operation.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Angioplasty / instrumentation*
  • Angioplasty / mortality*
  • Blood Vessel Prosthesis / statistics & numerical data*
  • Carotid Stenosis / diagnostic imaging
  • Carotid Stenosis / mortality*
  • Carotid Stenosis / surgery*
  • Embolic Protection Devices / statistics & numerical data*
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Prevalence
  • Radiography
  • Risk Factors
  • Stents / statistics & numerical data*
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome