[3-year follow-up after endovascular aneurysm treatment with Silk® flow diverter]

Rofo. 2013 Apr;185(4):328-32. doi: 10.1055/s-0032-1330353. Epub 2013 Feb 18.
[Article in German]

Abstract

Purpose: Flow diverters may occlude aneurysms by endoluminal reconstruction of the parent artery and by reducing the blood flow into the aneurysm. The purpose of this study was to assess the rate of intervention-associated complications and a 3-year-follow-up.

Materials and methods: We retrospectively analyzed 18 patients treated with Silk® FD. Only patients with unruptured aneurysms were included. Treatment indications were fusiform, giant or recurrent aneurysms. We considered all aneurysms to have a high likelihood of failure and/or recurrence when treated with conventional endovascular techniques.

Results: Silk FD could directly be placed in a proper position across the whole length of the aneurysm in 16/18 patients. In one case an additional PTA was necessary. In another case the first FD could not be properly deployed. 17 of 18 aneurysms (95 %) were occluded immediately, in the mid-term follow-up after 6 months or 3 years after treatment. The overall complication rate including technical (11.1 %), acute or delayed thromboembolic complication without (11.1 %) or with (16.6 %) severe complications was documented.

Conclusion: FD treatment is effective with a high occlusion rate of aneurysms also in long-term follow-up. In these complex aneurysms the complication rate is higher than in conventional stent-assisted coiling.

MeSH terms

  • Adult
  • Aged
  • Aspirin / administration & dosage
  • Cerebral Angiography
  • Clopidogrel
  • Embolization, Therapeutic
  • Equipment Design
  • Female
  • Humans
  • Intracranial Aneurysm / diagnosis
  • Intracranial Aneurysm / therapy*
  • Magnetic Resonance Angiography
  • Male
  • Middle Aged
  • Platelet Aggregation Inhibitors / administration & dosage
  • Premedication
  • Recurrence
  • Retreatment
  • Stents*
  • Surgical Instruments
  • Ticlopidine / administration & dosage
  • Ticlopidine / analogs & derivatives
  • Tomography, X-Ray Computed

Substances

  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine
  • Aspirin