Treatment of dystonia

Neurotherapeutics. 2014 Jan;11(1):139-52. doi: 10.1007/s13311-013-0231-4.

Abstract

Selecting the appropriate treatment for dystonia begins with proper classification of disease based on age, distribution, and underlying etiology. The therapies available for dystonia include oral medications, botulinum toxin, and surgical procedures. Oral medications are generally reserved for generalized and segmental dystonia. Botulinum toxin revolutionized the treatment of focal dystonia when it was introduced for therapeutic purposes in the 1980s. Surgical procedures are available for medication-refractory dystonia, markedly affecting an individual's quality of life.

Publication types

  • Review

MeSH terms

  • Anti-Dyskinesia Agents / therapeutic use*
  • Botulinum Toxins / therapeutic use
  • Dystonia / etiology
  • Dystonia / genetics
  • Dystonia / psychology
  • Dystonia / therapy*
  • Humans
  • Neurosurgery / methods*
  • Quality of Life
  • Trihexyphenidyl / therapeutic use

Substances

  • Anti-Dyskinesia Agents
  • Trihexyphenidyl
  • Botulinum Toxins