Thyroid doses and risk to paediatric patients undergoing neck CT examinations

Eur Radiol. 2015 Jul;25(7):1883-90. doi: 10.1007/s00330-015-3590-x. Epub 2015 Feb 2.

Abstract

Objective: To estimate thyroid doses and cancer risk for paediatric patients undergoing neck computed tomography (CT).

Methods: We used average CTDI(vol) (mGy) values from 75 paediatric neck CT examinations to estimate thyroid dose in a mathematical anthropomorphic phantom (ImPACT Patient CT Dosimetry Calculator). Patient dose was estimated by modelling the neck as mass equivalent water cylinder. A patient size correction factor was obtained using published relative dose data as a function of water cylinder size. Additional correction factors included scan length and radiation intensity variation secondary to tube-current modulation.

Results: The mean water cylinder diameter that modelled the neck was 14 ± 3.5 cm. The mathematical anthropomorphic phantom has a 16.5-cm neck, and for a constant CT exposure, would have thyroid doses that are 13-17% lower than the average paediatric patient. CTDI(vol) was independent of age and sex. The average thyroid doses were 31 ± 18 mGy (males) and 34 ± 15 mGy (females). Thyroid cancer incidence risk was highest for infant females (0.2%), lowest for teenage males (0.01%).

Conclusions: Estimated absorbed thyroid doses in paediatric neck CT did not significantly vary with age and gender. However, the corresponding thyroid cancer risk is determined by gender and age.

Key points: • Thyroid doses can be estimated from the CTDI(vol) in paediatric neck CT . • Scan length, neck size, and radiation intensity variation should be accounted for. • Estimated absorbed thyroid doses did not significantly vary with age and gender. • Thyroid cancer incidence risk is primarily determined by gender and age.

MeSH terms

  • Adolescent
  • Age Factors
  • Axis, Cervical Vertebra / diagnostic imaging
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Multidetector Computed Tomography / adverse effects*
  • Neck / diagnostic imaging*
  • Phantoms, Imaging
  • Radiation Dosage*
  • Radiometry / methods
  • Retrospective Studies
  • Risk
  • Sex Factors
  • South Carolina / epidemiology
  • Thyroid Gland / diagnostic imaging
  • Thyroid Neoplasms / epidemiology*