Intracranial Aneurysms in Children: The Role of Stenting and Flow-Diversion

J Neuroimaging. 2016 Jan-Feb;26(1):41-5. doi: 10.1111/jon.12305. Epub 2015 Oct 13.

Abstract

Objective: To report a single-center experience in the endovascular management of cerebral aneurysms in children with stenting and flow-diversion techniques.

Methods: During a 7-year period, 5 male patients with six intracranial aneurysms (IA) were treated by endovascular therapy with stenting or flow-diversion. The average age was 11 years (range 6-18 years).

Results: The etiology of the aneurysms was vasculopathic in 3 cases (50%), traumatic in 2 patients (33.3%), and idiopathic in 1 case (16.7%). Two-thirds of the aneurysms were giant in size. The aneurysms were most frequently located in the anterior circulation (66.7%). Fifty percent of the aneurysms were treated with stenting and coiling, and 50% were treated with flow-diversion stents alone. After treatment, occlusion was graded as: partial in five aneurysms (88.3%) and complete in 1 case (16.7%). Most cases (83.3%) had a good outcome after the procedure. During follow-up, most aneurysms had progressive occlusion (80%), while the rest were unchanged (20%). Most stents and flow-diverter devices remained patent (80%). However, one Pipeline flow-diverter device in the Anterior cerebral artery (ACA) A2 segment had an asymptomatic occlusion.

Conclusions: In this series, device-assisted endovascular techniques were a relatively safe and effective method of treatment of pediatric aneurysms. However, continued follow-up is required after treatment, because there are unsolved issues regarding the durability of flow-diverters and stents.

Keywords: Intracranial aneurysm; children; pipeline; stent.

MeSH terms

  • Adolescent
  • Cerebral Angiography*
  • Child
  • Embolization, Therapeutic / methods*
  • Endovascular Procedures / methods*
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / therapy
  • Male
  • Retrospective Studies
  • Stents*
  • Treatment Outcome