Differentiation of recurrent spinal ependymoma from postradiation treatment necrosis through multiparametric PET-MR and perfusion MRI

Clin Imaging. 2017 Jan-Feb:41:48-52. doi: 10.1016/j.clinimag.2016.09.002. Epub 2016 Sep 13.

Abstract

A 67-year-old male presented with papilledema and back pain localized to the T10 level. Initial workup revealed multifocal spinal ependymoma which was resected and treated with external beam radiotherapy. Nine years after treatment, the patient had a relapse of back pain, and MRI was inconclusive in distinguishing posttreatment radiation necrosis from recurrent tumor. We present the first described report with the utilization of multiparametric positron emission tomography-magnetic resonance imaging and perfusion MRI to distinguish recurrent spinal ependymoma from radiation necrosis.

Keywords: Multiparametric PET-MRI; Perfusion MRI; Radiation necrosis; Spinal ependymoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diagnosis, Differential
  • Ependymoma / diagnostic imaging*
  • Ependymoma / radiotherapy
  • Fluorodeoxyglucose F18
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Multimodal Imaging
  • Necrosis / diagnostic imaging
  • Neoplasm Recurrence, Local / diagnostic imaging*
  • Positron-Emission Tomography*
  • Radiation Injuries*
  • Radiopharmaceuticals
  • Spinal Neoplasms / diagnostic imaging*
  • Spinal Neoplasms / radiotherapy

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18