Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumors of the Nasal Cavity, Paranasal Sinuses and Skull Base

Edward B Stelow; Justin A Bishop

doi:10.1007/s12105-017-0791-4

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumors of the Nasal Cavity, Paranasal Sinuses and Skull Base

Head Neck Pathol. 2017 Mar;11(1):3-15. doi: 10.1007/s12105-017-0791-4. Epub 2017 Feb 28.

Authors

Edward B Stelow¹, Justin A Bishop²

Affiliations

¹ Department of Pathology, Anatomic Pathology, University of Virginia Health System, Jefferson Park Ave., Box 800214, Charlottesville, VA, 22908, USA. edstelow@yahoo.com.
² Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

Abstract

The sinonasal tract remains an epicenter of a diverse array of neoplasia. This paper discusses changes to the WHO classification system of tumors involving this area. In particular, seromucinous hamartoma, NUT carcinoma, biphenotypic sinonasal sarcoma, HPV-related carcinoma with adenoid cystic features, SMARCB1-deficient carcinoma, and renal cell-like adenocarcinoma are discussed.

Keywords: Adenoid cystic; Biphenotypical sinonasal sarcoma; Human papillomavirus; INI1; NUT carcinoma; Nasal; Seromucinous hamartoma; Sinonasal; Sinus; WHO.

MeSH terms

Humans
Nasal Cavity / pathology
Nose Neoplasms / classification*
Nose Neoplasms / pathology
Paranasal Sinus Neoplasms / classification*
Paranasal Sinus Neoplasms / pathology
Skull Base Neoplasms / classification*
Skull Base Neoplasms / pathology
World Health Organization