Diffusion weighted imaging for the detection and evaluation of cholesteatoma

World J Radiol. 2017 May 28;9(5):217-222. doi: 10.4329/wjr.v9.i5.217.

Abstract

Cholesteatoma is a collection of keratinous debris and stratified squamous epithelium. It is trapped in the middle ear and can lead to bony erosion. The disease is treated surgically often followed by a second-look procedure to check for residual tissue or recurrence. Cholesteatoma has specific signal-intensity characteristics on magnetic resonance imaging with very high signal intensity on diffusion weighted imaging (DWI). Various DWI techniques exist: Echo-planar imaging (EPI)-based and non-EPI-based techniques as well as new approaches like multi-shot EPI DWI. This article summarizes all techniques, discusses the significance in detecting cholesteatoma and mentions actual studies. Further recommendations for daily clinical practise are provided.

Keywords: Cholesteatoma; Computed tomography; Diffusion weighted imaging; Echo-planar imaging; Magnetic resonance imaging; Non-echo-planar imaging.

Publication types

  • Review