Molecular and clinical heterogeneity of adult diffuse low-grade IDH wild-type gliomas: assessment of TERT promoter mutation and chromosome 7 and 10 copy number status allows superior prognostic stratification

Acta Neuropathol. 2017 Dec;134(6):957-959. doi: 10.1007/s00401-017-1781-z. Epub 2017 Oct 19.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Brain Neoplasms / genetics*
  • Brain Neoplasms / metabolism*
  • Brain Neoplasms / pathology
  • Chromosomes, Human, Pair 10
  • Chromosomes, Human, Pair 7
  • DNA Copy Number Variations
  • Female
  • Follow-Up Studies
  • Glioma / genetics*
  • Glioma / metabolism*
  • Glioma / pathology
  • Humans
  • Isocitrate Dehydrogenase / genetics
  • Male
  • Middle Aged
  • Mutation
  • Neoplasm Grading
  • Prognosis
  • Promoter Regions, Genetic
  • Survival Analysis
  • Telomerase / genetics
  • Young Adult

Substances

  • Isocitrate Dehydrogenase
  • TERT protein, human
  • Telomerase