The NAIMS cooperative pilot project: Design, implementation and future directions

Jiwon Oh; Rohit Bakshi; Peter A Calabresi; Ciprian Crainiceanu; Roland G Henry; Govind Nair; Nico Papinutto; R Todd Constable; Daniel S Reich; Daniel Pelletier; William Rooney; Daniel Schwartz; Ian Tagge; Russell T Shinohara; Jack H Simon; Nancy L Sicotte; NAIMS Cooperative Steering Committee

doi:10.1177/1352458517739990

The NAIMS cooperative pilot project: Design, implementation and future directions

Mult Scler. 2018 Nov;24(13):1770-1772. doi: 10.1177/1352458517739990. Epub 2017 Nov 6.

Authors

Jiwon Oh¹, Rohit Bakshi², Peter A Calabresi³, Ciprian Crainiceanu³, Roland G Henry⁴, Govind Nair⁵, Nico Papinutto⁴, R Todd Constable⁶, Daniel S Reich⁵, Daniel Pelletier⁷, William Rooney⁸, Daniel Schwartz⁸, Ian Tagge⁸, Russell T Shinohara⁹, Jack H Simon⁸, Nancy L Sicotte¹⁰; NAIMS Cooperative Steering Committee

Affiliations

¹ Division of Neurology, University of Toronto, Toronto, ON, Canada/Department of Neurology and Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
² Laboratory for Neuroimaging Research, Partners Multiple Sclerosis Center, Departments of Neurology and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
³ Department of Neurology and Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
⁴ Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
⁵ Translational Neuroradiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Rockville, MD, USA.
⁶ Departments of Diagnostic Radiology and Neurosurgery, Yale University, New Haven, CT, USA.
⁷ Department of Neurology, University of Southern California, Los Angeles, CA, USA.
⁸ Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, USA.
⁹ Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
¹⁰ Department of Neurology, Cedars-Sinai Medical Center, The North American Imaging in Multiple Sclerosis (NAIMS), Los Angeles, CA, USA.

Abstract

The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic resonance imaging (MRI) research in multiple sclerosis (MS) through idea exchange and collaboration. Recently, NAIMS completed its first project evaluating the feasibility of implementation and reproducibility of quantitative MRI measures derived from scanning a single MS patient using a high-resolution 3T protocol at seven sites. The results showed the feasibility of utilizing advanced quantitative MRI measures in multicenter studies and demonstrated the importance of careful standardization of scanning protocols, central image processing, and strategies to account for inter-site variability.

Keywords: MRI; North America; collaboration.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Brain / diagnostic imaging*
Brain / pathology
Humans
Magnetic Resonance Imaging* / methods
Male
Middle Aged
Multicenter Studies as Topic
Multiple Sclerosis / diagnostic imaging*
Multiple Sclerosis / pathology
Pilot Projects
Reproducibility of Results

Abstract

Publication types

MeSH terms

Grants and funding