Abstract
Five patients with features of coexistent relapsing polychondritis and Behçet's disease are described. Review of the literature supports the overlap of the clinical manifestations of these two conditions. A common immunologic abnormality is likely, and elastin is cited as a possible target antigen. The "mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome" is the proposed name for this entity.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Autoantibodies / immunology
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Behcet Syndrome / complications*
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Behcet Syndrome / immunology
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Child
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Female
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Genital Diseases, Female / complications
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Genital Diseases, Male / complications
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Humans
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Male
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Middle Aged
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Mouth Diseases / complications
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Polychondritis, Relapsing / complications*
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Polychondritis, Relapsing / immunology
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Skin Ulcer / complications
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Ulcer / complications