Abstract
Novel nonionic contrast media were tested by injection into the subarachnoid space of the anterior fossae of guinea pigs, followed by EEG recording and histologic examination. Iopamidol was found to be more epileptogenic than metrizamide and P-297.
MeSH terms
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Animals
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Central Nervous System / diagnostic imaging
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Central Nervous System / drug effects*
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Central Nervous System / physiology
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Contrast Media / administration & dosage
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Contrast Media / toxicity*
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Electroencephalography
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Guinea Pigs
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Injections, Spinal
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Neuroradiography / methods
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Seizures / chemically induced*
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Solubility