Findings of the study on the dog hypogastric nerve regeneration after implantation in caudal large intestine distal region are presented. Not only occurrence of the implanted nerve structure repair was shown, but also its assistance to formation of a well-developed neurovascular plexus in large intestine wall. Regenerated nerve fibres from the nervous plexus that forms in the epineurium of the implanted nerve invade the wall of large intestine. These data indicate the formation of an intramural nervous apparatus in large intestine wall providing additional neurotrophic regulation of an organ.