Radiographic and morphologic studies of multiple miliary osteomas of cadaver skin

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Jul;86(1):121-5. doi: 10.1016/s1079-2104(98)90161-5.

Abstract

Objectives: The purpose of this study was to examine the frequency, chemical composition, and radiographic and morphologic features of multiple miliary osteomas of the facial skin.

Study design: Facial skin was obtained from 33 cadavers. After contact radiographs were taken, osteomas were examined by photo and scanning electron microscopy. Radiographic microanalysis of inorganic elements of the osteomas was also performed. In addition, clinical dental radiographic examinations were performed on 158 living subjects.

Results: Radiographic examination revealed milia-like osteomas in the facial skin of all of the cadavers. Nodules of 0.5 to 2.0 mm in diameter were scattered symmetrically in the skin of the cheek, mandibular angle, and forehead. Each nodule consisted of a concentric, multilamellated, osteoid cortex and an adipose medulla. Microanalysis suggested the presence of hydroxyapatite similar in composition to that of normal cortical bone. The condition was detected in 28% (44/158) of the living subjects by clinical dental radiographic examination.

Conclusion: Multiple miliary osteoma is a very common condition and may not be related to specific diseases.

MeSH terms

  • Adipose Tissue / pathology
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Bone Matrix / pathology
  • Cadaver
  • Calcium / analysis
  • Cheek
  • Durapatite / analysis
  • Facial Dermatoses / diagnostic imaging*
  • Facial Dermatoses / metabolism
  • Facial Dermatoses / pathology
  • Female
  • Forehead
  • Humans
  • Male
  • Mandible
  • Microscopy, Electron, Scanning
  • Middle Aged
  • Ossification, Heterotopic / diagnostic imaging*
  • Ossification, Heterotopic / metabolism
  • Ossification, Heterotopic / pathology
  • Phosphorus / analysis
  • Radiography, Dental
  • Sex Factors

Substances

  • Phosphorus
  • Durapatite
  • Calcium