Optical Systems for in Vivo Molecular Imaging of Cancer
…, J Aaron, B Hsu, D Nida, A Gillenwater… - … in cancer research …, 2003 - journals.sagepub.com
Progress toward a molecular characterization of cancer would have important clinical benefits;
thus, there is an important need to image the molecular features of cancer in vivo. In this …
thus, there is an important need to image the molecular features of cancer in vivo. In this …
Advances in fluorescence imaging techniques to detect oral cancer and its precursors
D Shin, N Vigneswaran, A Gillenwater… - Future …, 2010 - Future Medicine
Oral cancer is a significant health problem in the USA and throughout the world. Most oral
cancer patients are diagnosed at a late stage, when treatment is less successful and treatment-…
cancer patients are diagnosed at a late stage, when treatment is less successful and treatment-…
[HTML][HTML] Noninvasive diagnostic adjuncts for the evaluation of potentially premalignant oral epithelial lesions: current limitations and future directions
…, RR Richards-Kortum, AM Gillenwater… - Oral surgery, oral …, 2018 - Elsevier
Potentially premalignant oral epithelial lesions (PPOELs) are a group of clinically suspicious
conditions, of which a small percentage will undergo malignant transformation. PPOELs are …
conditions, of which a small percentage will undergo malignant transformation. PPOELs are …
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and …
…, C Heise, B Randlev, AM Gillenwater… - Nature medicine, 2000 - nature.com
ONYX-015 is an adenovirus with the E1B 55-kDa gene deleted, engineered to selectively
replicate in and lyse p53-deficient cancer cells while sparing normal cells. Although ONYX-…
replicate in and lyse p53-deficient cancer cells while sparing normal cells. Although ONYX-…
[HTML][HTML] IARC perspective on oral cancer prevention
…, DI Conway, A Gillenwater… - … England Journal of …, 2022 - Mass Medical Soc
IARC Perspective on Oral Cancer Prevention In a review of strategies for preventing oral
cancer, an expert panel reports that the use of tobacco (both smoking and smokeless), areca …
cancer, an expert panel reports that the use of tobacco (both smoking and smokeless), areca …
Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue
…, A El-Naggar, R Richards-Kortum, A Gillenwater - Clinical Cancer …, 2008 - AACR
Purpose: Autofluorescence imaging is increasingly used to noninvasively identify neoplastic
oral cavity lesions. Improving the diagnostic accuracy of these techniques requires a better …
oral cavity lesions. Improving the diagnostic accuracy of these techniques requires a better …
Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions
…, I Wistuba, KS Culotta, L Mao, A Gillenwater… - Cancer prevention …, 2009 - AACR
Epidemiologic and preclinical data support the oral cancer prevention potential of green tea
extract (GTE). We randomly assigned patients with high-risk oral premalignant lesions (OPL) …
extract (GTE). We randomly assigned patients with high-risk oral premalignant lesions (OPL) …
Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence
A Gillenwater, R Jacob, R Ganeshappa… - … –head & neck …, 1998 - jamanetwork.com
Objective To evaluate the clinical potential of fluorescence spectroscopy (a noninvasive
technique for assessing the chemical and morphologic composition of tissue) for in vivo …
technique for assessing the chemical and morphologic composition of tissue) for in vivo …
Merkel cell carcinoma of the head and neck: effect of surgical excision and radiation on recurrence and survival
AM Gillenwater, AC Hessel, WH Morrison… - … –Head & Neck …, 2001 - jamanetwork.com
Background Merkel cell carcinoma is a rare malignant neoplasm of the skin that most often
arises in the head and neck region. Despite the innocuous appearance of the primary lesion, …
arises in the head and neck region. Despite the innocuous appearance of the primary lesion, …
Objective detection and delineation of oral neoplasia using autofluorescence imaging
…, AK El-Naggar, JJ Lee, AM Gillenwater… - Cancer prevention …, 2009 - AACR
Although the oral cavity is easily accessible to inspection, patients with oral cancer most often
present at a late stage, leading to high morbidity and mortality. Autofluorescence imaging …
present at a late stage, leading to high morbidity and mortality. Autofluorescence imaging …