This article reviews the physical processes responsible for the transport and deposition of
particles and their theoretical modeling. Both laminar and turbulent processes are considered, …

Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However,
DNA copy number and gene expression signatures indicate differences between adult and …

We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

Aggressive human brain tumours (gliomas) often express a truncated and oncogenic form
of the epidermal growth factor receptor, known as EGFRvIII. Within each tumour only a small …

In the future, artificial intelligence (AI) is likely to substantially change both marketing
strategies and customer behaviors. Building from not only extant research but also extensive …

Tumors of the same histologic type often comprise clinically and molecularly distinct subgroups;
however, the etiology of these subgroups is unknown. Here, we report that histologically …

Proliferating embryonic and cancer cells preferentially use aerobic glycolysis to support
growth, a metabolic alteration commonly referred to as the “Warburg effect.” Here, we show that …

The brain tumor glioblastoma multiforme (GBM) is among the most lethal forms of human
cancer. Here, we report that a small subset of GBMs (3.1%; 3 of 97 tumors examined) harbors …

Despite the histological similarity of ependymomas from throughout the neuroaxis, the
disease likely comprises multiple independent entities, each with a distinct molecular …

Overexpression and activation of receptor tyrosine kinases, such as platelet derived growth
factor receptors (PDGFRs) and epidermal growth factor receptor (EGFR), leads to …