Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system

VA Levin, L Bidaut, P Hou, AJ Kumar, JS Wefel… - International Journal of …, 2011 - Elsevier
PURPOSE: To conduct a controlled trial of bevacizumab for the treatment of symptomatic
radiation necrosis of the brain. METHODS AND MATERIALS: A total of 14 patients were …

Paranasal sinuses: CT imaging requirements for endoscopic surgery.

…, DW Kennedy, AE Rosenbaum, BW Gayler, AJ Kumar… - Radiology, 1987 - pubs.rsna.org
Recent advances in the understanding of mucociliary activity and the pathophysiology of
the nasal cavity and paranasal sinuses have revolutionized the surgical management of …

Malignant gliomas: MR imaging spectrum of radiation therapy-and chemotherapy-induced necrosis of the brain after treatment

AJ Kumar, NE Leeds, GN Fuller, P Van Tassel… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To describe both the common and less frequently encountered magnetic
resonance (MR) imaging features of radiation therapy– and chemotherapy-induced brain injury, …

Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice

JF De Groot, G Fuller, AJ Kumar, Y Piao… - Neuro …, 2010 - academic.oup.com
Patients with recurrent malignant glioma treated with bevacizumab, a monoclonal antibody
to vascular endothelial growth factor (VEGF), alone or in combination with irinotecan have …

Effect of bevacizumab on radiation necrosis of the brain

J Gonzalez, AJ Kumar, CA Conrad, VA Levin - International Journal of …, 2007 - Elsevier
Purpose: Because blocking vascular endothelial growth factor (VEGF) from reaching leaky
capillaries is a logical strategy for the treatment of radiation necrosis, we reasoned that …

Basal ganglia volumes and white matter hyperintensities in patients with bipolar disorder.

…, JV Roberts-Twillie, PE Barta, AJ Kumar… - The American journal …, 1994 - europepmc.org
Objective Accumulating evidence suggests an association between abnormalities of the
basal ganglia and affective disorders. The authors hypothesized that patients with bipolar …

Characterization of benign and metastatic vertebral compression fractures with quantitative diffusion MR imaging

…, GC McKinnon, AJ Kumar - American journal of …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Conventional imaging techniques cannot be used to
unambiguously and reliably differentiate malignant from benign vertebral compression fractures. …

Phase II trial of the histone deacetylase inhibitor vorinostat (Zolinza™, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and …

…, VA Papadimitrakopoulou, C Lu, AJ Kumar… - Investigational new …, 2008 - Springer
This phase II trial was initiated to assess the efficacy and safety of oral vorinostat (Zolinza™,
suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head …

Tacrolimus‐associated posterior reversible encephalopathy syndrome after allogeneic haematopoietic stem cell transplantation

…, C Ippoliti, AD Forman, AJ Kumar… - British journal of …, 2003 - Wiley Online Library
Neurotoxicity is a significant complication of the use of tacrolimus. From April 1998 to December
2001, we identified 10 patients (six women, four men) who developed 11 episodes of …

Cortical magnetic resonance imaging changes in elderly inpatients with major depression.

…, GD Pearlson, E Aylward, AJ Kumar… - The American journal …, 1991 - europepmc.org
Objective The purpose of the study was to determine if magnetic resonance imaging (MRI)
scans of elderly depressed patients differ from MRI scans of age-matched control subjects …