The de novo DNA methyltransferase DNMT3A in development and cancer

BF Chen, WY Chan - Epigenetics, 2014 - Taylor & Francis
Chen et al. recently identified a novel short isoform-DNMT3A2 protein (about 82 kD).
Transcription of this isoform is initiated from a different promoter in the sixth intron of the DNMT3A …

High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases

BF Chen, CJ Liu, GM Jow, PJ Chen, JH Kao, DS Chen - Gastroenterology, 2006 - Elsevier
Background & Aims: The interactions among pre-S deletion, precore (PC) mutation, and basal
core promoter (BCP) mutation in various stages of chronic hepatitis B virus (HBV) infection …

[HTML][HTML] Hepatitis B virus pre-S/S variants in liver diseases

BF Chen - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Chronic hepatitis B is a global health problem. The clinical outcomes of chronic hepatitis B
infection include asymptomatic carrier state, chronic hepatitis (CH), liver cirrhosis (LC), and …

Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers

CJ Liu, BF Chen, PJ Chen, MY Lai… - The Journal of …, 2006 - academic.oup.com
BackgroundSeveral hepatitis B viral factors correlate with the progression of chronic liver
disease. However, the independent and interactive effects of each known viral factor on the …

Time-independent finite difference analysis of fully non-linear and viscous fluid sloshing in a rectangular tank

BF Chen, R Nokes - Journal of Computational Physics, 2005 - Elsevier
A novel, time-independent finite-difference method for analyzing complete two-dimensional
sloshing motion (surge, heave and pitch) in a tank has been developed based on the …

[HTML][HTML] An epigenetic regulator: methyl-CpG-binding domain protein 1 (MBD1)

L Li, BF Chen, WY Chan - International journal of molecular sciences, 2015 - mdpi.com
DNA methylation is an important form of epigenetic regulation in both normal development
and cancer. Methyl-CpG-binding domain protein 1 (MBD1) is highly related to DNA …

Zero-voltage-switching PWM resonant full-bridge converter with minimized circulating losses and minimal voltage stresses of bridge rectifiers for electric vehicle …

B Gu, CY Lin, BF Chen, J Dominic… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
This paper presents a zero-voltage-switching (ZVS) full-bridge dc-dc converter combing
resonant and pulse-width-modulation (PWM) power conversions for electric vehicle battery …

Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells

HI Lin, YJ Lee, BF Chen, MC Tsai, JL Lu, CJ Chou… - Cancer letters, 2005 - Elsevier
Beauvericin (BEA), a cyclic hexadepsipeptide from Codyceps cicadae, possesses anti-convulsion,
anti-arrhythmia, sedation, and anti-tumor activities. It has been reported that BEA …

Role of hepatitis B virus precore/core promoter mutations and serum viral load on noncirrhotic hepatocellular carcinoma: a case-control study

CJ Liu, BF Chen, PJ Chen, MY Lai… - The Journal of …, 2006 - academic.oup.com
BackgroundApart from the presence of liver cirrhosis, hepatitis B virus (HBV) factors have
also been shown to play a role in the development of hepatocellular carcinoma (HCC). …

Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway

X Chen, S Gu, BF Chen, WL Shen, Z Yin, GW Xu, JJ Hu… - Biomaterials, 2015 - Elsevier
Elucidating the regulatory mechanisms of osteogenesis of human mesenchymal stem cell (hMSC)
is important for the development of cell therapies for bone loss and regeneration. …