Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction …

The field of autoimmune encephalitides associated with antibodies targeting cell-surface
antigens is rapidly expanding and new antibodies are discovered frequently. Typical clinical …

Combining physical exercise with cognitive training is a popular intervention in dementia
prevention trials and guidelines. However, it remains unclear what combination strategies are …

Patient outcome in primary myelofibrosis (PMF) is significantly influenced by karyotype. We
studied 879 PMF patients to determine the individual and combinatorial prognostic relevance …

Janus kinase 2 (JAK2) mutations define polycythemia vera (PV). Calreticulin (CALR) and
myeloproliferative leukemia virus oncogene (MPL) mutations are specific to JAK2-unmutated …

… of an initial denaturation at 94 C for 2 min; 40 cycles of denaturation at 94 C for 15 s, annealing
at 56 C for 30 s, and extension at 72 C for 45 s; and final extension at 72 C for 1 min. PCR …

… BM aspirates and trephine sections were reviewed by one of us (C.-YL). All patients … ;
identified by § in Table 5) represent B- or C-findings and are therefore already accounted for in the …

High-throughput DNA sequence analysis was used to screen for TET2 mutations in bone
marrow-derived DNA from 239 patients with BCR-ABL-negative myeloproliferative neoplasms (…

… (C) No staining is observed of transfected cells probed with IgM-positive serum, but an
anti-IgG secondary antibody. (D–F) Higher magnification of NR1-transfected cells demonstrating …

… o C, followed by 35 cycles of 30 s at 94 o C, 45 s at 58 o C, and 45 s at 72 o C, followed by a
final step of 1 min at 72 o C… o C, followed by 35 cycles of 10 s at 94 o C, 45 s at 60 o C (0.2 o …