The mammalian brain is supplied with blood by specialized vasculature that is structurally
and functionally distinct from that of the periphery. A defining feature of this vasculature is a …

Intracarotid arterial hyperosmolar mannitol (ICAHM) blood–brain barrier disruption (BBBD)
is effective and safe for delivery of therapeutics for central nervous system malignancies. …

Please see the Editorial Comment by Veeranjaneyulu Prattipati discussing this article. With
the emergence of immune-modulating therapies, brain tumors present important diagnostic …

… CN Kersch is a MS student at TAMU partially supported by an Excellence Assistantship
from the College of Agriculture and Life Sciences. H.-L. … Kersch, PV Pietrantonio …

An improved understanding of the cellular and molecular biologic processes responsible for
brain tumor development, growth, and resistance to therapy is fundamental to improving …

Rationale and objective Poor clinical outcomes for patients with glioblastoma are in part
due to dysfunction of the tumor-immune microenvironment. An imaging approach able to …

Overexpression of O 6 -methylguanine DNA methyltransferase (MGMT) contributes to resistance
to chemo-radiation therapy (CRT) in brain tumors. We previously demonstrated that non…

Arthropod hormone receptors are potential targets for novel pesticides as they regulate
many essential physiological and behavioral processes. The majority of them belong to the …

BACKGROUND AND PURPOSE: Glioblastoma-associated macrophages are a major
constituent of the immune response to therapy and are known to engulf the iron-based MR …

Background Glioblastoma is a rapidly fatal brain cancer that exhibits extensive intra- and
intertumoral heterogeneity. Improving survival will require the development of personalized …