A precision measurement by the Alpha Magnetic Spectrometer on the International Space
Station of the positron fraction in primary cosmic rays in the energy range from 0.5 to 350 GeV …

Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular
space. These extracellular vesicles (EVs) contain materials that mirror the genetic and …

Immune-mediated anti-tumoral responses, elicited by oncolytic viruses and augmented with
checkpoint inhibition, may be an effective treatment approach for glioblastoma. Here in this …

Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1)
leads to cancer immune evasion via inhibition of T cell function. One of the defining …

Tumor-released RNA may mediate intercellular communication and serve as biomarkers.
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …

Studies of gene rearrangements and the consequent oncogenic fusion proteins have laid
the foundation for targeted cancer therapy. To identify oncogenic fusions associated with …

DNA damage activates a signalling network that blocks cell-cycle progression, recruits DNA
repair factors and/or triggers senescence or programmed cell death 1 . Alterations in …

Glioblastoma cells secrete extra-cellular vesicles (EVs) containing microRNAs (miRNAs).
Analysis of these EV miRNAs in the bio-fluids of afflicted patients represents a potential …

Exosomes found in the circulation are a primary source of important cancer-related RNA
and protein biomarkers that are expected to lead to early detection, liquid biopsy, and point-of-…

Background Litttle is known about the incidence of cancers of the small bowel. Methods Data
from cancer registries participating In the Surveillance, Epidemiology, and End-Results (…