The National Cancer Institute (NCI) sponsored a workshop to develop a set of standardized
diagnostic and response criteria for acute myeloid leukemia (AML) clinical trials. The French-…

Myelodysplastic and myeloproliferative disorders are rare in childhood and there is no widely
accepted system for their diagnosis and classification. We propose minimal diagnostic …

Multidrug resistance (MDR), especially that associated with overexpression of MDR1 and its
product, P-glycoprotein (Pgp), is thought to play a role in the outcome of therapy for some …

Brain aging research relies mostly on cross-sectional studies, which infer true changes from
age differences. We present longitudinal measures of five-year change in the regional brain …

An International Working Group met to revise the diagnostic and response criteria for acute
myelogenous leukemia originally published in 1990, as well as to provide definitions of …

In a prospective cross-sectional study, we used computerized volumetry of magnetic
resonance images to examine the patterns of brain aging in 148 healthy volunteers. The most …

… (D) By treatment arm for the intermediate cytogenetic risk group. (E) By treatment arm for the
… (D) By treatment arm for the intermediate cytogenetic risk group. (E) By treatment arm for the …

Cognitive decline is commonly observed in advanced aging even in the absence of disease.
Here we explore the possibility that normal aging is accompanied by disruptive alterations …

We conducted a retrospective analysis of 968 adults with acute myeloid leukemia (AML) on
5 recent Southwest Oncology Group trials to understand how the nature of AML changes …

… < 0.10); however, correlations with clinical outcome were largely performed using the D value
… analyzed with KS statistics and a D value of ≥ 0.25 was used to define a case as efflux (+). …