Hydrocephalus in children

KT Kahle, AV Kulkarni, DD Limbrick, BC Warf - The lancet, 2016 - thelancet.com
Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

…, W David, K Wang, SJ Schiff, DD Limbrick Jr… - Nature Reviews …, 2020 - nature.com
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 2: management of posthemorrhagic hydrocephalus in premature infants

…, AF Choudhri, KI Auguste, DD Limbrick… - Journal of …, 2014 - thejns.org
Object The objective of this systematic review and analysis was to answer the following
question: What are the optimal treatment strategies for posthemorrhagic hydrocephalus (PHH) in …

Decoding two-dimensional movement trajectories using electrocorticographic signals in humans

…, JG Ojemann, D Limbrick, D Moran… - Journal of neural …, 2007 - iopscience.iop.org
… Subject D had a right posterior temporal arteriovenous malformation embolized 20 years
earlier… They included three men (subjects A, C and D) and two women (subjects B and E). (See …

Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study

…, CN Shannon, MS Tamber, DD Limbrick… - Journal of …, 2016 - thejns.org
OBJECT The rate of CSF shunt failure remains unacceptably high. The Hydrocephalus Clinical
Research Network (HCRN) conducted a comprehensive prospective observational study …

On the role of the corpus callosum in interhemispheric functional connectivity in humans

…, A Mitra, JS Shimony, DD Limbrick… - Proceedings of the …, 2017 - National Acad Sciences
Resting state functional connectivity is defined in terms of temporal correlations between
physiologic signals, most commonly studied using functional magnetic resonance imaging. …

Resting-state activity in development and maintenance of normal brain function

…, AZ Snyder, JS Shimony, DD Limbrick… - Proceedings of the …, 2011 - National Acad Sciences
One of the most intriguing recent discoveries concerning brain function is that intrinsic
neuronal activity manifests as spontaneous fluctuations of the blood oxygen level–dependent (…

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

…, BC Warf, ER Smith, SJ Schiff, DD Limbrick Jr… - Nature medicine, 2020 - nature.com
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …

A new Hydrocephalus Clinical Research Network protocol to reduce cerebrospinal fluid shunt infection

…, DD Cochrane, AV Kulkarni, DD Limbrick… - Journal of …, 2016 - thejns.org
OBJECT In a previous report by the same research group (Kestle et al., 2011), compliance
with an 11-step protocol was shown to reduce CSF shunt infection at Hydrocephalus Clinical …

Outcomes of CSF shunting in children: comparison of Hydrocephalus Clinical Research Network cohort with historical controls

…, R Holubkov, JRW Kestle, DD Limbrick… - Journal of …, 2013 - thejns.org
Object The Hydrocephalus Clinical Research Network (HCRN), which comprises 7 pediatric
neurosurgical centers in North America, provides a unique multicenter assessment of the …