Determination of the therapeutic time window for human umbilical cord blood mononuclear cell transplantation following experimental stroke in rats

…, KG Reymann, M Strassburger, D Lobsien… - Cell …, 2012 - journals.sagepub.com
Experimental treatment strategies using human umbilical cord blood mononuclear cells (hUCB
MNCs) represent a promising option for alternative stroke therapies. An important point …

Reduced α4β2*–nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease

…, M Patt, D Sorger, F Wegner, D Lobsien… - Archives of general …, 2009 - jamanetwork.com
… In our subgroup analysis, patients in the D group exhibited the most pronounced differences
in α4β2*-nAChRbinding compared with healthy volunteers in the cingulate cortex and …

[HTML][HTML] Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small …

…, C Pösel, S Baasch, M Gawlitza, D Lobsien… - Acta neuropathologica …, 2014 - Springer
… In SHR, two-thirds of all T cells were rod-shaped while the rod-to-round ratio was almost 1:1
in WKY (D). Representative images of rod and round shaped T cells (green) in brain …

A systematic literature review and meta-analysis of the treatment of ruptured intracranial aneurysms with hydrophilic polymer and phosphorylcholine-coated flow …

…, J Klisch, DPO Kaiser, J Linn, L Pierot, D Lobsien - World Neurosurgery, 2023 - Elsevier
Objective Flow diverters coated with antithrombogenic substances were recently introduced
and have shown encouraging results in the preclinical setting. Our aim was to analyze their …

[HTML][HTML] A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes

…, S Frey, LD Collins, J Seeger, D Lobsien… - Frontiers in …, 2015 - frontiersin.org
Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic
coordinate systems have also been developed for experimental animals including non-…

Aneurysm treatment in acute SAH with hydrophilic-coated flow diverters under single-antiplatelet therapy: a 3-center experience

D Lobsien, C Clajus, D Behme… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In certain clinical circumstances, dual-antiplatelet therapy
can be problematic in patients with acute SAH. In some aneurysms, however, flow-diverting …

Altered serotonin transporter availability in patients with multiple sclerosis

S Hesse, F Moeller, D Petroff, D Lobsien… - European journal of …, 2014 - Springer
… Regional (volume-of-interest, VOI) analyses of DVRs was performed after coregistration with
3-D MRI data (T1-weighted MPRAGE, obtained on a 1.5-T Magnetom Symphony®; Siemens…

Preserved serotonin transporter binding in de novo Parkinson's disease: negative correlation with the dopamine transporter

…, S Hesse, GA Becker, M Patt, PM Meyer, D Lobsien… - Journal of …, 2011 - Springer
Recent imaging and neuropathological studies indicate reduced serotonin transporter (SERT)
in advanced Parkinson’s disease (PD). However, data on SERT in early PD patients are …

Simultaneous PET/MRI in stroke: a case series

…, B Sattler, T Jochimsen, D Lobsien… - Journal of Cerebral …, 2015 - journals.sagepub.com
Prospective studies on magnetic resonance imaging (MRI)-guided systemic thrombolysis
44.5 hours after stroke onset did not reach their primary end points. It was discussed and …

The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive–compulsive disorder

…, PM Meyer, J Luthardt, I Jahn, D Lobsien… - International Journal …, 2011 - academic.oup.com
The pathogenetic role of central serotonin transporters (SERT) in obsessive–compulsive
disorder (OCD) has been investigated in vivo by positron emission tomography (PET) or single-…