Biodiversity loss and its impact on humanity
The most unique feature of Earth is the existence of life, and the most extraordinary feature of
life is its diversity. Approximately 9 million types of plants, animals, protists and fungi inhabit …
life is its diversity. Approximately 9 million types of plants, animals, protists and fungi inhabit …
Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee …
…, E Goldmuntz, G McGee, CA Sable, D Srivastava… - Circulation, 2007 - Am Heart Assoc
The intent of this review is to provide the clinician with a summary of what is currently known
about the contribution of genetics to the origin of congenital heart disease. Techniques are …
about the contribution of genetics to the origin of congenital heart disease. Techniques are …
[HTML][HTML] Artificial intelligence to deep learning: machine intelligence approach for drug discovery
Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time consumption, …
companies and chemical scientists. However, low efficacy, off-target delivery, time consumption, …
[HTML][HTML] Adenovirus-associated virus vector–mediated gene transfer in hemophilia B
…, S Sleep, JM Cunningham, D Srivastava… - … England Journal of …, 2011 - Mass Medical Soc
Background Hemophilia B, an X-linked disorder, is ideally suited for gene therapy. We
investigated the use of a new gene therapy in patients with the disorder. Methods We infused a …
investigated the use of a new gene therapy in patients with the disorder. Methods We infused a …
[HTML][HTML] miR-126 regulates angiogenic signaling and vascular integrity
Precise regulation of the formation, maintenance, and remodeling of the vasculature is required
for normal development, tissue response to injury, and tumor progression. How specific …
for normal development, tissue response to injury, and tumor progression. How specific …
[HTML][HTML] Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
The reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) raises the possibility
that a somatic cell could be reprogrammed to an alternative differentiated fate without …
that a somatic cell could be reprogrammed to an alternative differentiated fate without …
Mutations in NOTCH1 cause aortic valve disease
…, R Barnes, IN King, PD Grossfeld, D Srivastava - Nature, 2005 - nature.com
… Garg and D. Srivastava for assistance with blood collection; G. Karsenty for Runx2
expression and p6OSE2 reporter plasmids; and L. Kedes for the GST–Hrt2 expression plasmid. …
expression and p6OSE2 reporter plasmids; and L. Kedes for the GST–Hrt2 expression plasmid. …
Biodiversity inventories, indicator taxa and effects of habitat modification in tropical forest
…, TB Larsen, NA Mawdsley, NE Stork, DS Srivastava… - Nature, 1998 - nature.com
… circles; flight-interception traps, open circles); d, canopy beetles; e, canopy ants (open squares
in d and e assume richness falls to zero in the absence of … DS Srivastava … DS Srivastava …
in d and e assume richness falls to zero in the absence of … DS Srivastava … DS Srivastava …
[HTML][HTML] Long-term safety and efficacy of factor IX gene therapy in hemophilia B
…, CL Morton, JT Gray, D Srivastava… - … England Journal of …, 2014 - Mass Medical Soc
Background In patients with severe hemophilia B, gene therapy that is mediated by a novel
self-complementary adeno-associated virus serotype 8 (AAV8) vector has been shown to …
self-complementary adeno-associated virus serotype 8 (AAV8) vector has been shown to …
Effects of biodiversity on the functioning of trophic groups and ecosystems
Over the past decade, accelerating rates of species extinction have prompted an increasing
number of studies to reduce species diversity experimentally and examine how this alters …
number of studies to reduce species diversity experimentally and examine how this alters …