Objective We sought to review the literature on cerebrospinal fluid (CSF) testing in patients
with COVID-19 for evidence of viral neuroinvasion by SARS-CoV-2. Methods We performed a …

The identification of heterozygous neomorphic isocitrate dehydrogenase (IDH) mutations
across multiple cancer types including both solid and hematologic malignancies has …

Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and may …

In 1995, C. David Marsden published an important paper entitled “Progressive myoclonic
ataxia associated with coeliac disease-The myoclonus is of cortical origin but the pathology is …

The repressive Hippo pathway has a profound tumour suppressive role in cancer by
restraining the growth-promoting function of the transcriptional coactivator, YAP. We previously …

High-throughput screening (HTS) of chemical libraries has become a critical tool in basic
biology and drug discovery. However, its implementation and the adaptation of high-content …

Characterizing complex viral transcriptomes by conventional RNA sequencing approaches
is complicated by high gene density, overlapping reading frames, and complex splicing …

… Therefore, I share the interest of Placantonakis et al. in this research. I hope that the present
retrospective study is a prelude to a prospective study that will help us to identify the safest …

Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains
unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and …

A methionine substitution at lysine-27 on histone H3 variants (H3K27M) characterizes ~80%
of diffuse intrinsic pontine gliomas (DIPG) and inhibits polycomb repressive complex 2 (…