[HTML][HTML] Atrial fibrillation in patients with cryptogenic stroke
…, V Hachinski, SB Coutts, DJ Sahlas… - … England Journal of …, 2014 - Mass Medical Soc
Background Atrial fibrillation is a leading preventable cause of recurrent stroke for which
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
CT angiography “spot sign” predicts hematoma expansion in acute intracerebral hemorrhage
R Wada, RI Aviv, AJ Fox, DJ Sahlas, DJ Gladstone… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— Morbidity and mortality in spontaneous intracerebral hemorrhage
(ICH) are correlated with hematoma progression. We hypothesized that the presence of …
(ICH) are correlated with hematoma progression. We hypothesized that the presence of …
Post-stroke depression, obstructive sleep apnea, and cognitive impairment: rationale for, and barriers to, routine screening
…, G Saposnik, Y Perez, DJ Sahlas… - … journal of stroke, 2016 - journals.sagepub.com
Stroke can cause neurological impairment ranging from mild to severe, but the impact of
stroke extends beyond the initial brain injury to include a complex interplay of devastating …
stroke extends beyond the initial brain injury to include a complex interplay of devastating …
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
…, D Roy, JL Rempel, ACR Rohr, D Iancu, DJ Sahlas… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion–derived blood flow and blood volume measurements
BD Murphy, AJ Fox, DH Lee, DJ Sahlas, SE Black… - Stroke, 2006 - Am Heart Assoc
Background and Purpose— We investigated whether computed tomography (CT) perfusion–derived
cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to …
cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to …
Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study
…, A Kirk, L Leach, A Robillard, DJ Sahlas… - Alzheimer's & …, 2018 - Wiley Online Library
Introduction Progress in understanding and management of vascular cognitive impairment (VCI)
has been hampered by lack of consensus on diagnosis, reflecting the use of multiple …
has been hampered by lack of consensus on diagnosis, reflecting the use of multiple …
The vascular impairment of cognition classification consensus study
…, A Kirk, L Leach, A Robillard, DJ Sahlas… - Alzheimer's & …, 2017 - Wiley Online Library
Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical
manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have …
manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have …
Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
…, Q Ibrahim, SI Bangdiwala, S Yusuf, S Tsai, DJ Sahlas… - The Lancet, 2019 - thelancet.com
Background In non-surgical settings, covert stroke is more common than overt stroke and is
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …
A new visual rating scale to assess strategic white matter hyperintensities within cholinergic pathways in dementia
Background and Purpose— One possible mechanism of cognitive decline in individuals with
subcortical vascular disease is disruption of cholinergic fibers by ischemic lesions, such as …
subcortical vascular disease is disruption of cholinergic fibers by ischemic lesions, such as …