EFNS‐ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease

R Schmidt, E Hofer, FH Bouwman… - European Journal of …, 2015 - Wiley Online Library
… Edith Hofer did the data synthesis and analysis and was part of the consensus finding process.
Femke H Bouwman, Katharina Buerger, Charlotte Cordonnier, Jan Laczó, Dorota Religa …

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

…, E Hofer, M Butkiewicz, B Fin, E Scarpini… - Nature …, 2019 - nature.com
Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …

Genome-wide association study identifies 74 loci associated with educational attainment

…, G Girotto, R Gupta, LM Hall, SE Harris, E Hofer… - Nature, 2016 - nature.com
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …

[HTML][HTML] A saturated map of common genetic variants associated with human height

…, P Hebbar, G Hindy, YLA Ho, E Hofer, E Holliday… - Nature, 2022 - nature.com
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50%
of phenotypic variation in human height, but identifying the specific variants and …

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

…, CA Hartman, AS Havulinna, AA Hicks, E Hofer… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis

E Hofer, B Schweighofer - Thrombosis and haemostasis, 2007 - thieme-connect.com
New vessel formation during development and in the adult is triggered by concerted signals
of largely endothelial-specific receptors for ligands of the VEGF, angiopoietin and ephrin …

[PDF][PDF] Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack

…, N Shussman, G Almogy, A Cuapio, E Hofer… - Immunity, 2015 - cell.com
Bacteria, such as Fusobacterium nucleatum, are present in the tumor microenvironment.
However, the immunological consequences of intra-tumoral bacteria remain unclear. Here, we …

Enlarged perivascular spaces and cognition: a meta-analysis of 5 population-based studies

…, M Habes, V Mok, N Venketasubramanian, E Hofer… - Neurology, 2018 - AAN Enterprises
… Seiler S, Pirpamer L, Hofer E, et al. Magnetization transfer ratio relates to cognitive impairment
in … Habes, and E. Hofer participated in data analysis and interpretation and revised the …

[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

…, E Hofer, MA Ikram, R Karlsson, E Knowles… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

A catalog of genetic loci associated with kidney function from analyses of a million individuals

…, JN Hellwege, CK Heng, AA Hicks, E Hofer… - Nature …, 2019 - nature.com
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …