… e, PLX7904 and vemurafenib inhibited the COLO205 xenograft growth (mean ± sem, eight
mice per group). f, B9 subcutaneous xenografts were stimulated by vemurafenib (*P < 0.05 by …

Objectives/Hypothesis: Human papillomavirus‐16 (HPV‐16)–associated carcinoma of the
oropharynx has a favorable prognosis. Such patients have elevated CD8+ T‐lymphocyte …

Background: The long-held axiom put forth by Hunter in 1743, that cartilage once injured is
incapable of healing, has been challenged by the technique of autologous chondrocyte …

… nucleus obtained in ultraviolet light should be markedly different from images obtained in the
red or nearinfrared. Such images … table 2 and the mass-to-light ratio is smaller than listed. …

… Two of the saponins, phytolaccosides B and E showed antifungal activity against the
human pathogenic opportunistic fungi. Phytolaccoside B had the broadest spectrum of activity …

The physiological effects of glucagon-like peptide-1 (GLP-1) are of immense interest because
of the potential clinical relevance of this peptide. Produced in intestinal L-cells through …

Neuroblastoma, the most common and deadly solid tumor in children, exhibits heterogeneous
clinical behavior, from spontaneous regression to relentless progression. Current …

ContextSingle-site studies suggest that a 2-week program of constraint-induced movement
therapy (CIMT) for patients more than 1 year after stroke who maintain some hand and wrist …

Background— Sildenafil was recently approved for the treatment of pulmonary arterial
hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in pulmonary …

Improvements in metabolite-profiling techniques are providing increased breadth of
coverage of the human metabolome and may highlight biomarkers and pathways in common …