Intima-media thickness (IMT) is increasingly used in clinical trials as a surrogate end point
for determining the success of interventions that lower risk factors for atherosclerosis. The …

a consistent observation over many years in hypertensive patients and animal models. 9, 10
In most vascular beds, not all microvessels are perfused at any one time; the fraction of …

Background: Earlier meta-analyses of small randomized trials suggested that mechanical
bowel preparation (MBP) should be omitted before colorectal surgery because it does not …

Intima-media thickness (IMT) provides a surrogate end point of cardiovascular outcomes in
clinical trials evaluating the efficacy of cardiovascular risk factor modification. Carotid artery …

Intima-media thickness (IMT) is increasingly used as a surrogate end point of vascular outcomes
in clinical trials aimed at determining the success of interventions that lower risk factors …

Background Malignant infarction of the middle cerebral artery (MCA) is associated with an
80% mortality rate. Non-randomised studies have suggested that decompressive surgery …

… Data were gathered with the use of electronic case report forms and kept at Unité de
Recherche Clinique (Lariboisière Hospital, Université Paris 7) under the supervision of the trial …

Few studies have directly compared the clinical features of neuropathic and non-neuropathic
pains. For this purpose, the French Neuropathic Pain Group developed a clinician-…

… Any imaging studies related to neurological adverse events are systematically collected
in electronic format and included in the material for independent clinical event adjudication. …

Background Patients' responses to oral antiplatelet therapy are subject to variation. Bedside
monitoring offers the opportunity to improve outcomes after coronary stenting by …