HIV, vascular risk factors, and cognition in the combination antiretroviral therapy era: a systematic review and meta-analysis
EC McIntosh, K Tureson, LJ Rotblatt… - Journal of the …, 2021 - cambridge.org
Objectives: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in
HIV and play a significant role in the development and persistence of HIV-associated …
HIV and play a significant role in the development and persistence of HIV-associated …
[HTML][HTML] Outcome after acute ischemic stroke is linked to sex-specific lesion patterns
…, BL Hancock, SJT Mocking, EC McIntosh… - Nature …, 2021 - nature.com
Acute ischemic stroke affects men and women differently. In particular, women are often
reported to experience higher acute stroke severity than men. We derived a low-dimensional …
reported to experience higher acute stroke severity than men. We derived a low-dimensional …
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases
T Krieg, Q Qin, EC McIntosh… - American Journal of …, 2002 - journals.physiology.org
Adenosine and acetylcholine (ACh) trigger preconditioning through different signaling pathways.
We tested whether either could activate myocardial phosphatidylinositol 3-kinase (PI3-…
We tested whether either could activate myocardial phosphatidylinositol 3-kinase (PI3-…
Importance of treatment status in links between type 2 diabetes and Alzheimer's disease
EC McIntosh, DA Nation… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE To investigate relationships among type 2 diabetes treatment, Alzheimer’s
disease(AD) biomarkers, and risk for dementia. RESEARCH DESIGN AND METHODS …
disease(AD) biomarkers, and risk for dementia. RESEARCH DESIGN AND METHODS …
Big data approaches to phenotyping acute ischemic stroke using automated lesion segmentation of multi-center magnetic resonance imaging data
…, MD Schirmer, RE Irie, SJT Mocking, EC McIntosh… - Stroke, 2019 - Am Heart Assoc
Background and Purpose— We evaluated deep learning algorithms’ segmentation of acute
ischemic lesions on heterogeneous multi-center clinical diffusion-weighted magnetic …
ischemic lesions on heterogeneous multi-center clinical diffusion-weighted magnetic …
[HTML][HTML] White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts–The MRI-GENIE study
…, MJ Nardin, SJT Mocking, EC McIntosh… - NeuroImage: Clinical, 2019 - Elsevier
White matter hyperintensity (WMH) burden is a critically important cerebrovascular phenotype
linked to prediction of diagnosis and prognosis of diseases, such as acute ischemic stroke …
linked to prediction of diagnosis and prognosis of diseases, such as acute ischemic stroke …
Ensemble of convolutional neural networks improves automated segmentation of acute ischemic lesions using multiparametric diffusion-weighted MRI
…, R Bezerra, MJRJ Bouts, EC McIntosh… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Accurate automated infarct segmentation is needed for acute
ischemic stroke studies relying on infarct volumes as an imaging phenotype or biomarker …
ischemic stroke studies relying on infarct volumes as an imaging phenotype or biomarker …
White matter hyperintensity burden in acute stroke patients differs by ischemic stroke subtype
…, KL Donahue, M Nardin, R Irie, EC McIntosh… - Neurology, 2020 - AAN Enterprises
Objective To examine etiologic stroke subtypes and vascular risk factor profiles and their
association with white matter hyperintensity (WMH) burden in patients hospitalized for acute …
association with white matter hyperintensity (WMH) burden in patients hospitalized for acute …
[HTML][HTML] Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
…, L Cloonan, R Irie, M Bouts, EC McIntosh… - Journal of …, 2020 - Springer
Objective Posterior circulation ischemic stroke (PCiS) constitutes 20–30% of ischemic
stroke cases. Detailed information about differences between PCiS and anterior circulation …
stroke cases. Detailed information about differences between PCiS and anterior circulation …
Design and rationale for examining neuroimaging genetics in ischemic stroke: The MRI-GENIE study
…, R Irie, S Winzeck, MJRJ Bouts, EC McIntosh… - Neurology …, 2017 - AAN Enterprises
Objective: To describe the design and rationale for the genetic analysis of acute and chronic
cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute …
cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute …