[HTML][HTML] Functional MRI and diffusion tensor imaging of brain reorganization after experimental stroke
…, K van der Marel, WM Otte, EI Hoff… - Translational stroke …, 2012 - Springer
The potential of the adult brain to reorganize after ischemic injury is critical for functional
recovery and provides a significant target for therapeutic strategies to promote brain repair. …
recovery and provides a significant target for therapeutic strategies to promote brain repair. …
Performance and complications of lumbar puncture in memory clinics: results of the multicenter lumbar puncture feasibility study
…, L Ghezzi, M Ingelsson, EI Hoff… - Alzheimer's & …, 2016 - Wiley Online Library
Introduction Lumbar puncture (LP) is increasingly performed in memory clinics. We investigated
patient‐acceptance of LP, incidence of and risk factors for post‐LP complications in …
patient‐acceptance of LP, incidence of and risk factors for post‐LP complications in …
Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease
SM Wong, JFA Jansen, CE Zhang, EI Hoff, J Staals… - Neurology, 2019 - AAN Enterprises
Objective To investigate the link between blood-brain-barrier (BBB) permeability and cerebral
blood flow (CBF) and the relation with white matter hyperintensities (WMH) in cerebral …
blood flow (CBF) and the relation with white matter hyperintensities (WMH) in cerebral …
Anosognosia in dementia: A review of current assessment instruments
…, B van Twillert, EI Hoff - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Anosognosia is a common but underrated symptom in dementia and has significant
impact on both patients and caregivers. A proper evaluation of anosognosia is therefore …
impact on both patients and caregivers. A proper evaluation of anosognosia is therefore …
White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed
…, EHBM Gronenschild, WM Palm, EI Hoff… - Neurobiology of …, 2020 - Elsevier
Blood-brain barrier (BBB) leakage is considered an important underlying process in both
cerebral small vessel disease (cSVD) and Alzheimer's disease (AD). The objective of this study …
cerebral small vessel disease (cSVD) and Alzheimer's disease (AD). The objective of this study …
[HTML][HTML] Blood–brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study
D Kerkhofs, SM Wong, E Zhang, R Uiterwijk, EI Hoff… - Geroscience, 2021 - Springer
Blood–brain barrier (BBB) dysfunction is one of the pathophysiological mechanisms in cerebral
small vessel disease (SVD). Previously, it was shown that BBB leakage volume is larger …
small vessel disease (SVD). Previously, it was shown that BBB leakage volume is larger …
MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO
…, ELA Blezer, EI Hoff… - Journal of Cerebral …, 2008 - journals.sagepub.com
Magnetic resonance imaging (MRI) has been applied to visualize monocyte infiltration with
the use of intravenously injected ultrasmall superparamagnetic iron oxide (USPIO). However, …
the use of intravenously injected ultrasmall superparamagnetic iron oxide (USPIO). However, …
[HTML][HTML] Associations of increased interstitial fluid with vascular and neurodegenerative abnormalities in a memory clinic sample
…, SM Wong, JJA de Jong, AA Postma, EI Hoff… - Neurobiology of …, 2021 - Elsevier
The vascular and neurodegenerative processes related to clinical dementia cause cell loss
which induces, amongst others, an increase in interstitial fluid (ISF). We assessed …
which induces, amongst others, an increase in interstitial fluid (ISF). We assessed …
Intravoxel incoherent motion imaging in small vessel disease: microstructural integrity and microvascular perfusion related to cognition
Background and Purpose— Cerebral small vessel disease (SVD) is associated with cognitive
impairment. This may be because of decreased microstructural integrity and microvascular …
impairment. This may be because of decreased microstructural integrity and microvascular …
Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer disease
BACKGROUND AND PURPOSE: Breakdown of BBB integrity occurs in dementia and may
lead to neurodegeneration and cognitive decline. We assessed whether extravasation of …
lead to neurodegeneration and cognitive decline. We assessed whether extravasation of …