[HTML][HTML] Functional MRI and diffusion tensor imaging of brain reorganization after experimental stroke

…, K van der Marel, WM Otte, EI Hoff… - Translational stroke …, 2012 - Springer
The potential of the adult brain to reorganize after ischemic injury is critical for functional
recovery and provides a significant target for therapeutic strategies to promote brain repair. …

Performance and complications of lumbar puncture in memory clinics: results of the multicenter lumbar puncture feasibility study

…, L Ghezzi, M Ingelsson, EI Hoff… - Alzheimer's & …, 2016 - Wiley Online Library
Introduction Lumbar puncture (LP) is increasingly performed in memory clinics. We investigated
patient‐acceptance of LP, incidence of and risk factors for post‐LP complications in …

Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease

SM Wong, JFA Jansen, CE Zhang, EI Hoff, J Staals… - Neurology, 2019 - AAN Enterprises
Objective To investigate the link between blood-brain-barrier (BBB) permeability and cerebral
blood flow (CBF) and the relation with white matter hyperintensities (WMH) in cerebral …

Anosognosia in dementia: A review of current assessment instruments

…, B van Twillert, EI Hoff - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Anosognosia is a common but underrated symptom in dementia and has significant
impact on both patients and caregivers. A proper evaluation of anosognosia is therefore …

White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed

…, EHBM Gronenschild, WM Palm, EI Hoff… - Neurobiology of …, 2020 - Elsevier
Blood-brain barrier (BBB) leakage is considered an important underlying process in both
cerebral small vessel disease (cSVD) and Alzheimer's disease (AD). The objective of this study …

[HTML][HTML] Blood–brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study

D Kerkhofs, SM Wong, E Zhang, R Uiterwijk, EI Hoff… - Geroscience, 2021 - Springer
Blood–brain barrier (BBB) dysfunction is one of the pathophysiological mechanisms in cerebral
small vessel disease (SVD). Previously, it was shown that BBB leakage volume is larger …

MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO

…, ELA Blezer, EI Hoff… - Journal of Cerebral …, 2008 - journals.sagepub.com
Magnetic resonance imaging (MRI) has been applied to visualize monocyte infiltration with
the use of intravenously injected ultrasmall superparamagnetic iron oxide (USPIO). However, …

[HTML][HTML] Associations of increased interstitial fluid with vascular and neurodegenerative abnormalities in a memory clinic sample

…, SM Wong, JJA de Jong, AA Postma, EI Hoff… - Neurobiology of …, 2021 - Elsevier
The vascular and neurodegenerative processes related to clinical dementia cause cell loss
which induces, amongst others, an increase in interstitial fluid (ISF). We assessed …

Intravoxel incoherent motion imaging in small vessel disease: microstructural integrity and microvascular perfusion related to cognition

…, SM Wong, R Uiterwijk, J Staals, WH Backes, EI Hoff… - Stroke, 2017 - Am Heart Assoc
Background and Purpose— Cerebral small vessel disease (SVD) is associated with cognitive
impairment. This may be because of decreased microstructural integrity and microvascular …

Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer disease

…, JF Jansen, HI Jacobs, EI Hoff… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Breakdown of BBB integrity occurs in dementia and may
lead to neurodegeneration and cognitive decline. We assessed whether extravasation of …