The emerging relationship between interstitial fluid–cerebrospinal fluid exchange, amyloid-β, and sleep
EL Boespflug, JJ Iliff - Biological psychiatry, 2018 - Elsevier
Amyloid-β (Aβ) plaques are a key histopathological hallmark of Alzheimer’s disease (AD),
and soluble Aβ species are believed to play an important role in the clinical development of …
and soluble Aβ species are believed to play an important role in the clinical development of …
Brain-mapping techniques for evaluating poststroke recovery and rehabilitation: a review
JC Eliassen, EL Boespflug, M Lamy… - Topics in stroke …, 2008 - Taylor & Francis
Brain-mapping techniques have proven to be vital in understanding the molecular, cellular,
and functional mechanisms of recovery after stroke. This article briefly summarizes the …
and functional mechanisms of recovery after stroke. This article briefly summarizes the …
Concord grape juice supplementation and neurocognitive function in human aging
R Krikorian, EL Boespflug, DE Fleck… - Journal of agricultural …, 2012 - ACS Publications
Polyphenol compounds found in berry fruits, in particular flavonoids, have been associated
with health benefits including improvement in cognition and neuronal function with aging. …
with health benefits including improvement in cognition and neuronal function with aging. …
Enhanced neural activation with blueberry supplementation in mild cognitive impairment
EL Boespflug, JC Eliassen, JA Dudley… - Nutritional …, 2018 - Taylor & Francis
Objectives: Preclinical studies have shown that blueberry supplementation can improve
cognitive performance and neural function in aged animals and have identified associations …
cognitive performance and neural function in aged animals and have identified associations …
[HTML][HTML] Fish oil supplementation increases event-related posterior cingulate activation in older adults with subjective memory impairment
EL Boespflug, RK McNamara, JC Eliassen… - The Journal of nutrition …, 2016 - Elsevier
Objective To determine the effects of long-chain omega-3 (LCn-3) fatty acids found in fish oil,
including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on cortical blood …
including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on cortical blood …
Venous collagenosis as pathogenesis of white matter hyperintensity
Objective Periventricular white matter hyperintensities (pvWMHs) are commonly observed on
MRI in older individuals and are associated with cognitive and motor decline. The etiology …
MRI in older individuals and are associated with cognitive and motor decline. The etiology …
Baseline NAWM structural integrity and CBF predict periventricular WMH expansion over time
N Promjunyakul, HH Dodge, D Lahna, EL Boespflug… - Neurology, 2018 - AAN Enterprises
Objective We aimed to describe and compare baseline cerebral blood flow (CBF) and
microstructural characteristics of normal-appearing white matter (NAWM) within the vulnerable …
microstructural characteristics of normal-appearing white matter (NAWM) within the vulnerable …
Improved cognitive-cerebral function in older adults with chromium supplementation
R Krikorian, JC Eliassen, EL Boespflug… - Nutritional …, 2010 - Taylor & Francis
Insulin resistance is implicated in the pathophysiological changes associated with Alzheimer's
disease, and pharmaceutical treatments that overcome insulin resistance improve …
disease, and pharmaceutical treatments that overcome insulin resistance improve …
Targeted assessment of enlargement of the perivascular space in Alzheimer's disease and vascular dementia subtypes implicates astroglial involvement specific to …
EL Boespflug, MJ Simon, E Leonard… - Journal of …, 2018 - content.iospress.com
… All vessel-wise quantification was completed by a research assistant (EL) blind to clinical
group status. For each subject, the perivascular space was evaluated at ten large caliber (…
group status. For each subject, the perivascular space was evaluated at ten large caliber (…
MR imaging–based multimodal autoidentification of perivascular spaces (mMAPS): automated morphologic segmentation of enlarged perivascular spaces at clinical …
Purpose To describe a fully automated segmentation method that yields object-based
morphologic estimates of enlarged perivascular spaces (ePVSs) in clinical-field-strength (3.0-T) …
morphologic estimates of enlarged perivascular spaces (ePVSs) in clinical-field-strength (3.0-T) …