[HTML][HTML] Immune evasion in cancer: Mechanistic basis and therapeutic strategies
Cancer immune evasion is a major stumbling block in designing effective anticancer
therapeutic strategies. Although considerable progress has been made in understanding how …
therapeutic strategies. Although considerable progress has been made in understanding how …
[HTML][HTML] Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults
In this study we used stool profiling to identify intestinal bacteria and metabolites that are
differentially represented in humans with colorectal cancer (CRC) compared to healthy controls …
differentially represented in humans with colorectal cancer (CRC) compared to healthy controls …
Macrophage-and dendritic cell—dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF
Macrophages and dendritic cells play an important role in regulating B-cell responses, including
proliferation to antigens such as trinitrophenyl (TNP)—Ficoll and TNP-Brucella abortus. …
proliferation to antigens such as trinitrophenyl (TNP)—Ficoll and TNP-Brucella abortus. …
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex
…, WR Matson, E Storey, P Milbury, EA Ryan… - Journal of the …, 1992 - Elsevier
Huntington's disease (HD) is characterized by gradually evolving selective neuronal death.
Several lines of evidence suggest that an excitotoxic mechanism may play a role. Tryptophan …
Several lines of evidence suggest that an excitotoxic mechanism may play a role. Tryptophan …
Mechanisms of cancer-related fatigue
JL Ryan, JK Carroll, EP Ryan, KM Mustian… - The …, 2007 - academic.oup.com
Cancer-related fatigue (CRF) is one of the most prevalent symptoms patients with cancer
experience, both during and after treatment. CRF is pervasive and affects patients' quality of life …
experience, both during and after treatment. CRF is pervasive and affects patients' quality of life …
[HTML][HTML] Cancer-and cancer treatment–associated cognitive change: an update on the state of the science
TA Ahles, JC Root, EL Ryan - Journal of Clinical Oncology, 2012 - ncbi.nlm.nih.gov
Cognitive changes associated with cancer and cancer treatments have become an
increasing concern. Using breast cancer as the prototype, we reviewed the research from …
increasing concern. Using breast cancer as the prototype, we reviewed the research from …
Best method in clinical practice and in research studies to determine left atrial size
SJ Lester, EW Ryan, NB Schiller, E Foster - The American journal of …, 1999 - Elsevier
Although the anteroposterior dimension of the left atrium is universally used in clinical
practice and research, we hypothesized that it may be an inaccurate surrogate for volume …
practice and research, we hypothesized that it may be an inaccurate surrogate for volume …
[HTML][HTML] Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection
…, AM Berlin, CM Malboeuf, EM Ryan… - PLoS …, 2012 - journals.plos.org
Deep sequencing technologies have the potential to transform the study of highly variable
viral pathogens by providing a rapid and cost-effective approach to sensitively characterize …
viral pathogens by providing a rapid and cost-effective approach to sensitively characterize …
[HTML][HTML] Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine
Background The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …
falciparum and has partial protective efficacy against clinical and severe malaria disease in …
A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner
…, KP Curry, SW Renner, A Greenwalt, EP Ryan… - Cancer discovery, 2014 - AACR
Whether dietary fiber protects against colorectal cancer is controversial because of conflicting
results from human epidemiologic studies. However, these studies and mouse models of …
results from human epidemiologic studies. However, these studies and mouse models of …