Clinical picture of EPM1‐Unverricht‐Lundborg disease

…, K Eriksson, R Vanninen, E Mervaala - …, 2008 - Wiley Online Library
Unverricht‐Lundborg disease (ULD), progressive myoclonic epilepsy type 1 (EPM1,
OMIM254800), is an autosomal recessively inherited neurodegenerative disorder characterized by …

[HTML][HTML] Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus

…, L Niskanen, J Lehtinen, E Mervaala… - … England Journal of …, 1995 - Mass Medical Soc
Background There is little information on the incidence and natural history of neuropathy in
patients with non-insulin-dependent diabetes mellitus (NIDDM). Methods We studied patients …

Quantitative MRI of the hippocampus and amygdala in severe depression

E Mervaala, J Föhr, M Könönen… - Psychological …, 2000 - cambridge.org
Background. There is little evidence to support possible structural changes in the amygdala
and hippocampus of patients with severe depression.Methods. Quantitative MRI of the …

Unverricht‐Lundborg disease

…, M Korja, MK Lehtinen, E Mervaala… - Epileptic …, 2016 - Wiley Online Library
We first review the clinical presentation and current therapeutic approaches available for
treating Unverricht‐Lundborg disease (ULD), a progressive myoclonus epilepsy. Next, we …

Comparison of navigated and non-navigated transcranial magnetic stimulation for motor cortex mapping, motor threshold and motor evoked potentials

…, N Danner, E Niskanen, T Hukkanen, E Mervaala… - Neuroimage, 2009 - Elsevier
Transcranial magnetic stimulation (TMS) can be used for non-invasive assessment of
cortical physiology and descending motor pathways. However, the focus/exact site of cortical …

Human brain connectivity during single and paired pulse transcranial magnetic stimulation

…, S Määttä, D Ponzo, F Ferrarelli, G Tononi, E Mervaala… - Neuroimage, 2011 - Elsevier
OBJECTIVE: Intracortical inhibition (SICI) and facilitation (ICF) in the human motor cortex
can be measured using a paired pulse transcranial magnetic stimulation (ppTMS) protocol. …

Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea–hypopnea index

A Kulkas, P Tiihonen, P Julkunen, E Mervaala… - Medical & biological …, 2013 - Springer
Sleep apnea–hypopnea syndrome (SAHS) causes impairment of daytime functions and
increases risk of cardiovascular diseases. Apnea–hypopnea index (AHI), currently used for the …

Sensorimotor cortex excitability and connectivity in Alzheimer's disease: A TMS‐EEG co‐registration study

…, D Ponzo, S Määtta, E Mervaala… - Human brain …, 2016 - Wiley Online Library
Several studies have shown that, in spite of the fact that motor symptoms manifest late in the
course of Alzheimer's disease (AD), neuropathological progression in the motor cortex …

Motor potentials evoked by navigated transcranial magnetic stimulation in healthy subjects

…, T Lohioja, J Nurkkala, E Mervaala… - Journal of clinical …, 2008 - journals.lww.com
Navigated transcranial magnetic stimulation (TMS) is a tool for targeted, noninvasive stimulation
of cerebral cortex. Transcranial stimuli can depolarize neurons and evoke measurable …

The severity of individual obstruction events is related to increased mortality rate in severe obstructive sleep apnea

…, T Hukkanen, P Tiihonen, E Mervaala… - Journal of Sleep …, 2013 - Wiley Online Library
Obstructive sleep apnea ( OSA ) is linked to an increased mortality rate. However, the severity
of individual obstruction events is rarely considered quantitatively in clinical practice. We …