Background and Purpose— About one half of those who develop adult-onset moyamoya
disease experience intracranial hemorrhage. Despite the extremely high frequency of …

We analysed the epidemiological data and clinical features of patients with prion diseases
that had been registered by the Creutzfeldt-Jakob Disease Surveillance Committee, Japan, …

A decrease in intracellular glutathione content may be related to the primary event in
Parkinson's disease, so increasing the glutathione level may have a therapeutic benefit. The …

Background and Purpose— The primary results of the Japan Adult Moyamoya Trial revealed
the statistically marginal superiority of bypass surgery over medical treatment alone in …

In this study, we investigate the neurotoxicity of glycation, particularly early‐stage glycation,
and its mechanisms, which are possibly synergized with oxidative stress. Methylglyoxal (MG) …

… The backward elimination technique was used, whereby all variables were entered into
the equation, then sequentially removed if the probability of its F value was > 0-05. The …

Facial palsy occurred in 21 (19.6%) of 107 Japanese patients with multiple sclerosis (MS)
during a mean follow-up period of 4.3 years. We observed residual signs of facial palsy in five …

The nationwide epidemiological survey of syringomyelia was carried out in Japan by sending
inquiries to neurologists, child neurologists, neurosurgeons and orthopedic surgeons for …

We evaluated the pathogenicity of mercury (Hg) and selenium (Se) which are supposed to
be one of the risk factors in the development of amyotrophic lateral sclerosis (ALS). Hg and …

We investigated the effects of two reactive dicarbonyl compounds, methylglyoxal (MG) and 3-deoxyglucosone
(3-DG), on cultured spinal cord neurons. Incubation of cortical and spinal …