The flow of activity in the cortical microcircuitry is poorly understood. We use calcium imaging
to reconstruct, with millisecond and single-cell resolution, the spontaneous activity of …

… as ΔF/F = (F 1 − F 0 )/F 0 , expressed in %, where F 1 is fluorescence at any time point and F
0 is … To detect followers online, we computed a ΔF/F movie and adjusted the look-up table so …

Purpose The mechanisms of cerebral aneurysm rupture are not fully understood. We
analyzed the associations of hemodynamics, morphology, and patient age and gender with …

Gap junctions have been postulated to exist between the axons of excitatory cortical
neurons based on electrophysiological, modeling, and dye-coupling data. Here, we provide …

Neocortical circuits share anatomical and physiological similarities among different species
and cortical areas. Because of this, a ‘canonical’ cortical microcircuit could form the …

Purpose Unruptured cerebral aneurysms pose a dilemma for physicians who need to weigh
the risk of a devastating subarachnoid hemorrhage against the risk of surgery or …

The understanding of any neural circuit requires the identification and characterization of all
its components. Morphologic classifications of neurons are, therefore, of central importance …

BACKGROUND AND PURPOSE: Hostile hemodynamic conditions and geometries are thought
to predispose aneurysms for instability and rupture. This study compares stable, unstable…

BACKGROUND AND PURPOSE: Cerebral aneurysms in the posterior circulation are known
to have a higher rupture risk than those in the anterior circulation. We sought to test the …

BACKGROUND AND PURPOSE: Different hemodynamic patterns have been associated
with aneurysm rupture. The objective was to test whether hemodynamic characteristics of the …