Imaging of opioid receptors in the central nervous system

G Henriksen, F Willoch - Brain, 2008 - academic.oup.com
In vivo functional imaging by means of positron emission tomography (PET) is the sole
method for providing a quantitative measurement of μ-, κ and δ-opioid receptor-mediated …

Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain—an fMRI analysis

M Valet, T Sprenger, H Boecker, F Willoch, E Rummeny… - Pain, 2004 - Elsevier
Neuroimaging studies with positron emission tomography (PET) and functional magnetic
resonance imaging (fMRI) have delineated a human pain network in vivo. Despite the …

Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study

…, H Siebner, M Riemenschneider, F Willoch… - European journal of …, 2003 - Springer
… In all subjects, an intravenous bolus of 370 MBq 18 F-FDG was injected at rest with the
eyes closed. PET imaging started 30 min after tracer injection. Scans were performed under …

Region‐specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis

…, F Munz, W Zieglgänsberger, F Willoch… - Annals of neurology …, 1999 - Wiley Online Library
… four multivariate analyses of variance for pain intensity [F(1,11) … for unpleasantness
ratings and the order of pain stimulation in the time course of the experiment [F(2,10) 13.85, p …

Lasting cortical activation after repetitive TMS of the motor cortex: a glucose metabolic study

HR Siebner, M Peller, F Willoch, S Minoshima… - Neurology, 2000 - AAN Enterprises
Objective: Cerebral [ 18 F]fluorodeoxy-d-glucose PET ([ 18 F]FDG-PET) was used to
visualize the lasting neuronal activation after repetitive transcranial magnetic stimulation (rTMS) …

Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C] diprenorphine PET study

F Willoch, F Schindler, HJ Wester, M Empl, A Straube… - Pain, 2004 - Elsevier
Based on concepts that endogenous opioids participate in neural transmission of pain, the
present study in central poststroke pain (CPSP) patients investigated changes in opioid …

Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (18F) Positron Emission Tomography/Computerized Tomography …

…, S Fanti, DM Schuster, F Willoch - The Journal of …, 2017 - auajournals.org
… A total of 596 patients underwent fluciclovine ( 18 F) positron … The positive predictive value
of fluciclovine ( 18 F) positron … Fluciclovine ( 18 F) was well tolerated and the safety profile …

Rewards of beauty: the opioid system mediates social motivation in humans

…, J Riegels, G Løseth, H Maurud, F Willoch… - Molecular …, 2014 - nature.com
… increase in ‘wanting’ behavior after morphine relative to naltrexone treatment (F (2,1206)
=5.2, P=0.006, M>… The main effect of drug did not reach significance (F (2,1314) =1.8, P=0.16). …

Statistical brain mapping of 18F-FDG PET in Alzheimer's disease: validation of anatomic standardization for atrophied brains

K Ishii, F Willoch, S Minoshima, A Drzezga… - Journal of Nuclear …, 2001 - Soc Nuclear Med
… Thirty minutes after injection of 370 MBq 18 F-FDG, a sequence of three 10-min frames
was acquired and later summated into a single frame. Images were reconstructed by filtered …

[PDF][PDF] Quantitative assessment of cerebral blood flow in patients with Alzheimer's disease by SPECT

…, S Minoshima, C Hirsch, K Buch, F Willoch… - Journal of Nuclear …, 1997 - Soc Nuclear Med
¡ ncortical association areas showed a significant correlation with an overall level of cognitive
decline, as assessed by the Mini Mental State Examination and by the cognitive section …