Cerebral white matter of asymptomatic people frequently exhibits circumscribed areas of
hyperintensity on magnetic resonance (MR) images and hypodensity on computed tomography …

Background Cerebral aging is a complex and heterogeneous process that is associated
with a high degree of inter‐individual variability. Structural magnetic resonance imaging (MRI) …

We examined age-, sex-, and hemisphere-related differences in the cerebral cortex. Volumes
of the cerebral hemispheres and 13 regions of interest (ROIs) were measured on magnetic …

To examine putative brain substrates of cognitive functions differentially affected by age, the
authors measured the volume of cortical regions and performance on tests of executive …

Neuroanatomical substrates of age-related differences in working memory and perseverative
behavior were examined in a sample of healthy adults (50–81 years old). The participants, …

Sex differences have been observed in neurobehavioral measures and in neuroanatomic
studies. Men and women differ in emotion processing, including perception, experience and …

Advancing age is associated with significant declines on neurobehavioral tasks that demand
substantial mental effort. Functional imaging studies of mental abilities indicate that older …

BACKGROUND: Executive dysfunction is common in geriatric depression and persists after
improvement of depressive symptoms. This study examined the relationship of executive …

n-back letter and fractal tasks were administered to II participants during functional magnetic
resonance imaging to test process specificity theories of prefrontal cortex (PFC) function …

Objective: White matter abnormalities may interfere with limbic cortical balance and lead to
chronic depressive syndromes. The authors used diffusion tensor imaging to test the …